Why the study?
Does pulsed Doppler echocardiography accurately measure beat-to-beat changes in stroke volume compared to an electromagnetic flowmeter in open-chest dogs?
Does pulsed Doppler echocardiography accurately measure beat-to-beat changes in stroke volume compared to an electromagnetic flowmeter in open-chest dogs?
Pulsed Doppler echocardiography provides an excellent measurement of stroke volume changes in an open-chest dog model, though clinical application may be limited.
Supports Doppler echocardiography for experimental stroke volume assessment in dogs; leaves open clinical translation for beat-to-beat monitoring.
Measurement of stroke volume by pulsed Doppler echocardiography has not been validated against a reference method in vivo. We compared Doppler systolic frequency shift integrals with electromagnetic flowmeter stroke volume in seven open-chest dogs. A pulsed Doppler echocardiographic transducer was held on the aortic arch with the sample volume in the ascending aorta. Stroke volume was varied by epinephrine or pentobarbital infusions, fluid administration or inferior vena caval construction. Linear regression analysis of stroke volume vs Doppler systolic frequency shift integrals revealed strong correlations and intercepts close to zero (tau = 0.74-0.096, rho less than 0.001). Minor changes in transducer position did not influence Doppler frequency shift integrals substantially. Therefore, pulsed Doppler echocardiography served as an excellent measurement of stroke volume changes in model. However, serious limitations are presented that may limit its clinical application.
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Steingart et al. (1980) studied this question.
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