Why the study?
Does coronary vasodilation to sublingual nitroglycerine measured by CMR differ between asymptomatic high-risk patients and age-matched controls?
Population
46 asymptomatic subjects, including 13 high-risk patients and 33 age-matched controls.
Comparison
Sublingual nitroglycerine with coronary… vs Age-matched controls receiving the same NTG and…
Design
Case-control
Authors
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Impaired coronary NTG vasodilation on CMR was associated with DM/ESRD; leaves open its value as a functional atherosclerosis marker pending prospective studies.
Does coronary vasodilation to sublingual nitroglycerine measured by CMR differ between asymptomatic high-risk patients and age-matched controls?
Noninvasive coronary CMR can detect impaired coronary vasodilation to nitroglycerine in asymptomatic high-risk patients, potentially serving as a functional indicator of subclinical atherosclerosis.
Nguyen et al. (2008) studied this question.
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