Why the study?
Does levosimendan improve renal function and hemodynamics in patients with acute decompensated heart failure and moderate renal impairment?
Population
21 patients with acute decompensated heart failure, moderate renal impairment, pulmonary capillary wedge…
Comparison
Infusion of levosimendan added to standard therapy vs Placebo added to standard therapy
Design
RCT, randomized
Follow-up
72 hours
Authors
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Supports levosimendan for renal protection in acute decompensated HF with moderate impairment; extends cardiorenal evidence beyond hemodynamics.
Does levosimendan improve renal function and hemodynamics in patients with acute decompensated heart failure and moderate renal impairment?
Levosimendan provides immediate renoprotective effects and improves renal hemodynamics in patients with acute decompensated heart failure and renal impairment.
Fedele et al. (2013) studied this question.
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