April 12, 2011Clinical and Applied Thrombosis/Hemostasis

A New Rapid Method to Measure Human Platelet Cholesterol

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Population

47 healthy participants, plus 3 participants for repeatability and 2 for reproducibility testing.

Authors

IJI.A. JagroopThe Royal Free Hospital JPJahm Want PersaudRoyal Free London NHS Foundation Trust DMDimitri P. MikhailidisThe Royal Free Hospital

Discussion

Member takes

Implication

Enables further platelet cholesterol research; leaves open clinical utility pending larger validation studies.

Structured PICO

Population

47 healthy participants, plus 3 participants for repeatability and 2 for reproducibility testing.

Intervention

A new rapid method to measure platelet cholesterol using freeze-thaw and sonication cycles to disrupt a platelet pellet.

Outcome

Repeatability, reproducibility, and correlation of platelet cholesterol with serum lipid parameters (TC, LDL-C, HDL-C, TG, non-HDL-C).surrogate

A newly developed, rapid method for measuring platelet cholesterol is reproducible and correlates significantly with serum atherogenic lipid profiles.

Limitations

More extensive evaluation is necessary

Cite This Study

Jagroop et al. (2011) studied this question.

synapsesocial.com/papers/6a8294975bcab2ccdb8d5f2d https://doi.org/10.1177/1076029611404213

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Ask AI

Bookmark

A New Rapid Method to Measure Human Platelet Cholesterol

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

A New Rapid Method to Measure Human Platelet Cholesterol

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider