Population
Ca channels of skeletal muscle transverse tubules incorporated into planar lipid bilayers
Comparison
Dihydropyridines (agonistBay K 8644 and 9… vs Internal vs external application
Design
Preclinical
Authors
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No immediate clinical implications from this animal study; leaves open dual-sided DHP receptor coupling in skeletal muscle calcium channels.
Calcium channels of skeletal muscle appear to be functionally coupled to two dihydropyridine receptor sites on opposite sides of the membrane.
Valdivia et al. (1990) studied this question.
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