Why the study?
Does anti-Xa activity >1 IU/mL correlate with increased bleeding risk in patients on heparin with APTT >180 s?
Population
47 patients treated with continuous intravenous infusion of heparin for management of thromboembolic…
Comparison
Anti-Xa activity >1 IU/mL vs Anti-Xa activity <1 IU/mL
Design
Cohort
Follow-up
during the time of heparin therapy
Authors
Loading...
May warrant anti-Xa monitoring in supratherapeutic APTT patients; hypothesis-generating and requires prospective validation before guiding practice.
Does anti-Xa activity >1 IU/mL correlate with increased bleeding risk in patients on heparin with APTT >180 s?
In patients on heparin with APTT >180 s, anti-Xa activity >1 IU/mL is associated with a significantly higher risk of bleeding complications compared to anti-Xa <1 IU/mL.
Haliassos et al. (1997) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: