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November 1, 1984Journal of Applied Physiology

Cardiopulmonary reflexes and blood pressure in exercising sinoaortic-denervated dogs

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Population

Conscious dogs with chronic sinoaortic denervation

Comparison

Bilateral cervical vagotomy combined with 12 min… vs Before vagotomy during the same exercise protocols

Design

Preclinical

Authors

DDDimitris A. DaskalopoulosWomen & Children's Hospital of BuffaloJSJohn T. ShepherdCross-Cutting CardiologySWS. C. Walgenbach

Discussion

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Implication

Vagal afferents may stabilize post-exercise BP without baroreflexes; leaves open translation to human autonomic regulation.

Structured PICO

P
Population
Conscious dogs with chronic sinoaortic denervation
I
Intervention
Bilateral cervical vagotomy (interruption of cardiopulmonary afferents) combined with 12 min of light exercise and 12 min of graded exercise
C
Comparator
Before vagotomy (intact cardiopulmonary afferents) during the same exercise protocols
O
Outcome
Arterial blood pressure during and after exercisesurrogate

In the chronic absence of arterial baroreflexes, vagal afferents prevent a rise in arterial blood pressure after vigorous exercise.

Cite This Study

Daskalopoulos et al. (1984) studied this question.

synapsesocial.com/papers/6a829d926a677a72e121da0chttps://doi.org/10.1152/jappl.1984.57.5.1417
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiopulmonary reflexes and arterial pressure during rest and exercise in dogs1983 · 38 citations
  2. 2Inhibition by carotid baroreflex of exercise-induced increases in arterial pressure.1983 · 133 citations
  3. 3Sinoaortic contribution to ventilatory control in exercising dogs1983 · 1 citations
  4. 4The influence of cardiopulmonary receptors on long‐term blood pressure control and plasma renin activity in conscious dogs1987 · 11 citations
  5. 5Hypertension following denervation of aortic baroreceptors in unanesthetized dogs.1979 · 41 citations