February 2, 2017Journal of the American Heart AssociationOpen Access

Less Than Ideal Cardiovascular Health Is Associated With Shorter Leukocyte Telomere Length: The National Health and Nutrition Examination Surveys, 1999–2002

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Why the study?

Is less-than-ideal cardiovascular health associated with shorter leukocyte telomere length in adults?

Structured PICO

Is less-than-ideal cardiovascular health associated with shorter leukocyte telomere length in adults?

Population

5194 adults (aged ≥20) from the National Health and Nutrition Examination Survey 1999-2002

Intervention

Poor or intermediate cardiovascular health (CVH) based on 7 AHA metrics (smoking, physical activity, diet, body mass index, blood pressure, total cholesterol, and fasting blood glucose)

Comparator

Ideal cardiovascular health (CVH)

Outcome

Leukocyte telomere length (LTL) assayed from whole bloodsurrogate

Less-than-ideal cardiovascular health is associated with shorter leukocyte telomere length, suggesting a link between cardiovascular risk factors and cellular aging.

Discussion

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Implication

Should not change CVH management; hypothesis-generating for links between risk factors and cellular aging.

Cite This Study

Gebreab et al. (2017) studied this question.

synapsesocial.com/papers/6a829ea6409efddc54d4a5b6 https://doi.org/10.1161/jaha.116.004105

Topics

Women and heart disease

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Less Than Ideal Cardiovascular Health Is Associated With Shorter Leukocyte Telomere Length: The National Health and Nutrition Examination Surveys, 1999–2002

Structured PICO

Discussion

Implication

Cite This Study

Topics

Less Than Ideal Cardiovascular Health Is Associated With Shorter Leukocyte Telomere Length: The National Health and Nutrition Examination Surveys, 1999–2002

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider