September 1, 1999Journal of Hypertension

Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension

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Population

257 pregnant women, comprising 178 normotensive subjects and 79 gravidas with pregnancy-induced hypertension.

Design

Cohort

Follow-up

From the 8th to the 36th week of pregnancy

Authors

KZK ZafirovskaPediatric Nephrology of Alabama VMVesela T. MaleskabInstitute of public health of Republic of Macedonia SBS. BogdanovskaPediatric Nephrology of Alabama

Discussion

Member takes

Implication

hANP rise may compensate in PIH; leaves open prognostic value or therapeutic targeting.

Structured PICO

Population

257 pregnant women, comprising 178 normotensive subjects and 79 gravidas with pregnancy-induced hypertension (PIH).

Comparator

Normotensive pregnant subjects

Outcome

Plasma levels of human atrial natriuretic peptide (hANP), endothelin-1 (ET-1), plasma-renin activity (PRA), and 24-h urinary excretion of aldosterone (U-Ald) measured at the 8th, 18th, 23rd, 28th, 32nd, and 36th weeks of pregnancy.surrogate

Elevated human atrial natriuretic peptide in pregnancy-induced hypertension may act as a compensatory mechanism against active vasopressors and sodium retention.

Cite This Study

Zafirovska et al. (1999) studied this question.

synapsesocial.com/papers/6a82a0fc8aa2f088808d5e15 https://doi.org/10.1097/00004872-199917090-00012

Topics

Hypertension management

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Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider