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March 4, 2021Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of CardiologyOpen Access

Epicardial adipose tissue volume predicts long term major adverse cardiovascular events in patients with Type 2 diabetes

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Why the study?

Epicardial adipose tissue is metabolically active and plays an important role in coronary atherosclerosis, but its relationship with long-term MACE in patients with T2-DM without prior coronary events required investigation.

Population

127 patients with T2-DM without previous coronary events who underwent CCTA

Comparison

Patients who experienced MACE vs those who did not

Design

Retrospective cohort study

Follow-up

60±7 months

Authors

BUBegüm UygurÖÇÖmer ÇelikADAli Rıza Demir

Discussion

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Member takes

Overview

EAT volume may aid MACE risk stratification in T2DM; hypothesis-generating and requires prospective validation before clinical use.

Structured PICO

P
Population
127 patients with Type 2 diabetes mellitus (T2-DM) without previous coronary events who underwent coronary computed tomography angiography (CCTA) between 2012 and 2014
I
Intervention
Epicardial adipose tissue (EAT) volume measurement by coronary computed tomography angiography (CCTA)
O
Outcome
Major adverse cardiovascular events (MACE), defined as cardiac death, non-fatal myocardial infarction or unstable angina requiring hospitalization, coronary revascularizations (percutaneous coronary intervention or coronary artery bypass grafting surgery), heart failure, peripheral arterial disease, or ischemic strokecomposite

Epicardial adipose tissue volume measured by CCTA is an independent predictor of long-term major adverse cardiovascular events in patients with Type 2 diabetes without prior coronary events, offering additional risk stratification value.

Cite This Study

Uygur et al. (2021) studied this question.

synapsesocial.com/papers/6a82b1cdf5f149803a21e69dhttps://doi.org/10.5543/tkda.2021.65635
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