Enteroviral infection outbreaks in pediatric hematology-oncology units can lead to severe complications including fatal encephalitis.
Alerts clinicians to fatal enteroviral encephalitis risk in pediatric heme-onc units; case reports leave optimal prevention strategies open.
We review the clinical courses and outcomes of an outbreak of enteroviral infection that occurred in 5 children with acute lymphoblastic leukemia during a 2-month period in a hematology-oncology unit. Three patients presented with encephalitis and 2 with parotitis. Three of the 5 patients recovered uneventfully and 2 died, 1 of chronic encephalitis and 1 of acute brain stem encephalitis.
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Moschovi et al. (2002) studied this question.
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