Management of extracranial atherosclerotic cerebrovascular disease involves risk factor modification for asymptomatic patients, with the addition of medical or surgical therapies for symptomatic patients.
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Reinforces symptom-stratified management of extracranial cerebrovascular disease; leaves open need for contemporary RCTs to refine intervention thresholds.
Extracranial atherosclerotic cerebrovascular disease is a risk factor for myocardial infarction and stroke. Asymptomatic patients with evidence of disease may benefit from modification of risk factors for stroke (ie, hypertension, hyperlipidemia, diabetes mellitus, and cigarette smoking). Symptomatic patients with focal brain ischemia may benefit from antiplatelet therapy, anticoagulation, and surgery in addition to modification of risk factors.
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Efrain Salgado (1991) studied this question.
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