Why the study?
Does nitrendipine compared to enalapril reduce blood pressure in patients with mild to moderate essential hypertension?
Population
44 patients with mild to moderate essential hypertension
Comparison
Nitrendipine (2(1–4(1 mg daily) as monotherapy vs Enalapril (20–40 mg daily) as monotherapy
Design
RCT, double-blind
Follow-up
16 weeks
Authors
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Nitrendipine matches enalapril for BP lowering in mild-moderate hypertension; confirms equivalent monotherapy efficacy in this RCT.
Does nitrendipine compared to enalapril reduce blood pressure in patients with mild to moderate essential hypertension?
Nitrendipine and enalapril are equally effective as monotherapy for mild to moderate essential hypertension, with their use limited primarily by specific side effects rather than lack of efficacy.
Verkaaik et al. (1991) studied this question.
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