Why the study?
Does prolonged sevoflurane anesthesia at low fresh gas flow rates cause renal injury due to Compound A exposure compared to other anesthetics or high flow rates?
Population
Surgical patients receiving anesthesia, as well as human volunteers and animal models exposed to sevoflurane…
Comparison
Sevoflurane anesthesia, particularly prolonged… vs Comparative anesthetics or high fresh gas flow…
Design
Editorial
Authors
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This editorial supports the FDA warning that prolonged sevoflurane anesthesia at low fresh gas flow rates should be avoided due to the risk of Compound A-induced renal tubular injury.
Does prolonged sevoflurane anesthesia at low fresh gas flow rates cause renal injury due to Compound A exposure compared to other anesthetics or high flow rates?
This editorial supports the FDA warning that prolonged sevoflurane anesthesia at low fresh gas flow rates should be avoided due to the risk of Compound A-induced renal tubular injury.
Bedford et al. (2000) studied this question.
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