Why the study?
Does sevoflurane compared to desflurane increase markers of renal injury in fluid-restricted volunteers?
Population
19 fluid-restricted (nothing by mouth overnight) volunteers
Comparison
8 hours of 1.25 minimum alveolar anesthetic… vs 8 hours of 1.25 MAC desflurane given in a…
Design
Cohort
Follow-up
5-7 days
Authors
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Caution advised with sevoflurane in fluid-restricted patients; leaves open clinical relevance of transient renal markers versus desflurane.
Does sevoflurane compared to desflurane increase markers of renal injury in fluid-restricted volunteers?
Sevoflurane anesthesia at 2 L/min for 8 hours in fluid-restricted volunteers is associated with transient renal and hepatic injury compared to desflurane.
Eger et al. (1997) studied this question.