July 4, 2019IUBMB Life
Familial combined hyperlipidemia: An overview of the underlying molecular mechanisms and therapeutic strategies
Why the study?
Familial combined hyperlipidemia is an important cause of cardiovascular disease with high prevalence, making targeted treatment ideal, but this requires understanding patients' genetic background and underlying metabolic pathways.
Design
Review
Authors
Discussion
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Member takes
Implication
Provides synthesis of FCHL pathways and therapies; leaves open validation of novel treatments in trials.
Structured PICO
P
Population
Patients with familial combined hyperlipidemia (FCHL)
I
Intervention
Existing and novel treatment options for FCHL
This review summarizes the molecular mechanisms, genetic background, and therapeutic strategies for familial combined hyperlipidemia.
Cite This Study
Taghizadeh et al. (2019) studied this question.