Why the study?
Does the LPL S447X polymorphism influence changes in body composition and LPL activity in response to endurance training in adult subjects?
Population
741 adult white and black subjects
Comparison
20 weeks of endurance training vs Noncarriers of the X447 allele
Design
Cohort
Follow-up
20 weeks
Authors
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Should not yet change exercise prescriptions; hypothesis-generating for sex- and race-specific LPL variant effects on training responses.
Does the LPL S447X polymorphism influence changes in body composition and LPL activity in response to endurance training in adult subjects?
The LPL S447X polymorphism influences training-induced changes in body fat and LPL activity in women, but not in men.
Garenc et al. (2001) studied this question.
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