Why the study?
Does LPL gene variation (HindIII and S447X polymorphisms) affect postprandial lipoprotein metabolism in healthy males?
Population
51 healthy male volunteers
Comparison
Vitamin A-fat load test consisting of 1 g fat/kg… vs Comparison between different LPL genotypes
Design
Cross-sectional
Follow-up
11 hours
Authors
Loading...
LPL S447X variation may modulate CAD risk via postprandial lipemia; hypothesis-generating, requires prospective validation before any clinical use.
Does LPL gene variation (HindIII and S447X polymorphisms) affect postprandial lipoprotein metabolism in healthy males?
LPL gene variations significantly influence postprandial lipoprotein metabolism, which may explain the lower risk of coronary artery disease associated with the H1X447 genotype.
López‐Miranda et al. (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: