Why the study?
Although catheter-directed thrombolysis reduces post-thrombotic syndrome risk, it remains unclear which patient groups should receive it given the risk of bleeding.
Does catheter-directed thrombolysis improve outcomes compared to anticoagulation alone in adults with proximal deep vein thrombosis?
Population
175 patients aged ≥18 years with proximal DVT
Comparison
Catheter-directed thrombolysis vs anticoagulant therapy alone
Design
Retrospective study
Follow-up
At least 30 days
Authors
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May support CDT for iliac DVT clearance without excess bleeding; leaves open clinical outcome benefits pending randomized trials.
Does catheter-directed thrombolysis improve outcomes compared to anticoagulation alone in adults with proximal deep vein thrombosis?
Catheter-directed thrombolysis improves thrombus clearance rates compared to anticoagulation alone in proximal DVT, particularly in iliac vein thrombosis, without increasing bleeding or mortality, though it prolongs hospitalization.
Sarıcaoğlu et al. (2025) studied this question.
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