Why the study?
Does catheter-directed thrombolysis plus anticoagulation reduce in-hospital mortality compared to anticoagulation alone in patients with proximal deep vein thrombosis?
Does catheter-directed thrombolysis plus anticoagulation reduce in-hospital mortality compared to anticoagulation alone in patients with proximal deep vein thrombosis?
In patients with proximal DVT, catheter-directed thrombolysis plus anticoagulation did not improve in-hospital mortality compared to anticoagulation alone, but was associated with significantly higher rates of adverse events including intracranial hemorrhage and increased hospital costs.
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CDT shows no mortality advantage in proximal DVT; leaves open net benefit and safety in randomized trials.
Bashir et al. (2014) studied this question.
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