Key result
Resveratrol administration to hypertensive diabetic rats significantly reduced oxidative stress and inflammation, improving vascular reactivity and left ventricular pump function.
Why the study?
Does resveratrol prevent cardiovascular complications in spontaneously hypertensive streptozotocin-induced diabetic rats?
Does resveratrol prevent cardiovascular complications in spontaneously hypertensive streptozotocin-induced diabetic rats?
Resveratrol preserves cardiovascular function in a combined rat model of hypertension and diabetes by reducing oxidative stress and inflammation, independent of glycemic or hemodynamic changes.
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Does not support clinical use; extends preclinical evidence for resveratrol in hypertensive diabetic models.
Vella et al. (2015) studied Hypertension and diabetes. Resveratrol was evaluated on Oxidative stress, lipid peroxidation, inflammation, and cardiovascular function. Resveratrol administration to hypertensive diabetic rats significantly reduced oxidative stress and inflammation, improving vascular reactivity and left ventricular pump function.
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