Key result
Hypertension in overweight/obese type 2 diabetes patients was associated with increased insulin resistance (OGIS 267 vs 342.89, p<0.01) and higher IL-6 levels (15.46 vs 11.77, p<0.05).
Why the study?
Is hypertension in obese/overweight type 2 diabetes patients associated with increased insulin resistance and pro-inflammatory cytokines?
Population
75 individuals: 30 type 2 diabetes patients with increased body weight and hypertension, 30 T2D patients…
Design
Cross-sectional
Authors
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Should not yet change practice; leaves open whether hypertension drives insulin resistance and IL-6 in obese T2D.
Cross-Sectional (n=75)
Is hypertension in obese/overweight type 2 diabetes patients associated with increased insulin resistance and pro-inflammatory cytokines?
Absolute Event Rate: 267% vs 342.89%
p-value: p=<0.01
Hypertension in overweight/obese type 2 diabetes patients is associated with increased insulin resistance and elevated IL-6 levels, suggesting a potential target for preventive interventions.
Lukić et al. (2014) conducted a cross-sectional in Type 2 diabetes with obesity and hypertension (n=75). Hypertension vs. Normotension was evaluated on Insulin resistance (OGIS index) (p=<0.01). Hypertension in overweight/obese type 2 diabetes patients was associated with increased insulin resistance (OGIS 267 vs 342.89, p<0.01) and higher IL-6 levels (15.46 vs 11.77, p<0.05).
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