Population
Wistar and spontaneously hypertensive rats (SHR)
Comparison
Microinjection of angiotensin II into the… vs Wistar rats
Design
Preclinical
Authors
Loading...
May implicate RVLM AT1 receptors in sympathetic hyperactivity; leaves open relevance to human hypertension.
Higher expression of AT1 receptors in the RVLM of spontaneously hypertensive rats may contribute to their increased responsiveness to angiotensin II, activating sympathetic pathways.
Hu et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: