Key result
Central angiotensin II in the brainstem modulates sympathetic responses and baroreflex control in both the short and long term, increasing the range of adaptive response patterns.
Population
Preclinical models (rabbits)
Design
Review
Authors
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Should not yet guide clinical autonomic management; leaves open targeted research on brainstem angiotensin II pathways in hypertension and HF.
This review highlights the physiological role of central angiotensin II in modulating sympathetic nerve activity and baroreflex control mechanisms.
Head et al. (2001) conducted a review in Cardiovascular regulation. Central Angiotensin II was evaluated. Central angiotensin II in the brainstem modulates sympathetic responses and baroreflex control in both the short and long term, increasing the range of adaptive response patterns.