April 1, 1995The Journal of Clinical Endocrinology & Metabolism

Insulin-like growth factor (IGF)-I and -II and IGF-binding proteins-1, -2, and -3 in children and adolescents with diabetes mellitus: correlation with metabolic control and height attainment.

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Population

58 patients (age, 0.8-17 yr) with treated (n=51) or untreated (n=7) insulin-dependent diabetes mellitus (IDDM)

Design

Cross-sectional

Authors

BSB Strasser-VogelLudwig-Maximilians-Universität München WBWerner BlumUniversity of Kassel RPR. PastMünchen Klinik

Discussion

Member takes

Implication

May warrant growth monitoring in diabetic youth with elevated HbA1c; leaves open whether IGF-IGFBP modulation improves outcomes.

Structured PICO

Population

58 patients (age, 0.8-17 yr) with treated (n=51) or untreated (n=7) insulin-dependent diabetes mellitus (IDDM)

Comparator

Normal subjects (healthy controls)

Outcome

Serum levels of IGF-I, IGF-II, and IGFBP-1, -2, and -3surrogate

IDDM in children and adolescents is associated with alterations in the IGF-IGFBP system, which correlate with metabolic control and may contribute to growth impairment.

Cite This Study

Strasser-Vogel et al. (1995) studied this question.

synapsesocial.com/papers/6a82d8be9aaf5d32a4b28e7e https://doi.org/10.1210/jcem.80.4.7536202

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Insulin-like growth factor (IGF)-I and -II and IGF-binding proteins-1, -2, and -3 in children and adolescents with diabetes mellitus: correlation with metabolic control and height attainment.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Insulin-like growth factor (IGF)-I and -II and IGF-binding proteins-1, -2, and -3 in children and adolescents with diabetes mellitus: correlation with metabolic control and height attainment.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider