Why the study?
Does decreasing pressure in the aortic arch or carotid sinuses affect abdominal vascular capacitance and resistance in dogs?
Population
Chloralose-anesthetized dogs
Comparison
Decrease in pressure in the vascularly isolated… vs Constant pressure in the carotid sinus or aortic…
Design
Preclinical
Authors
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Extends baroreflex control of splanchnic capacitance in dogs; leaves open translation to human cardiovascular regulation.
Does decreasing pressure in the aortic arch or carotid sinuses affect abdominal vascular capacitance and resistance in dogs?
Decreases in aortic arch pressure reflexively decrease abdominal vascular capacitance and increase resistance, mediated by venous and splanchnic nerves.
Karim et al. (1978) studied this question.
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