Why the study?
Does elevation of pressure in the isolated aortic arch affect respiratory movements and cardiac function in anesthetized dogs?
Population
Anesthetized dogs
Comparison
Stepwise pressure variations in the isolated… vs Baseline or lower aortic arch pressures
Design
Preclinical
Authors
Loading...
No direct clinical implications; leaves open translation of aortic arch baroreflex effects to human physiology.
Does elevation of pressure in the isolated aortic arch affect respiratory movements and cardiac function in anesthetized dogs?
Aortic arch baroreceptor stimulation via elevated pressure reflexively depresses respiratory movements and cardiac function in a canine model, mediated by both parasympathetic and sympathetic pathways.
Levy et al. (1966) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: