Key result
Compared with aortic Doppler ultrasound, Modelflow pulse contour analysis underestimated stroke volume by up to 25% after standing from a squat and 16% after thigh-cuff release (P<0.05).
Why the study?
Modelflow has been validated in steady-state conditions, but its validity for estimating stroke volume during dynamic changes in physiological state, such as active orthostatic stress testing, was unknown.
Does Modelflow accurately estimate stroke volume compared to aortic Doppler ultrasound during rapid changes in blood pressure in adults?
Population
15 adults (six females)
Comparison
Modelflow vs aortic Doppler ultrasound vs bioelectrical impedance analysis
Design
Physiological comparative study
Authors
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Caution advised with Modelflow for stroke volume during rapid BP shifts; leaves open its validity versus aortic Doppler.
Observational (n=15)
Does Modelflow accurately estimate stroke volume compared to aortic Doppler ultrasound during rapid changes in blood pressure in adults?
p-value: p=< 0.05
Pulse contour analysis (Modelflow) significantly underestimates stroke volume during rapid physiological changes in blood pressure compared to aortic Doppler ultrasound, suggesting it should be interpreted with caution in dynamic states.
Gibbons et al. (2018) conducted an observational in Orthostatic stress (n=15). Modelflow (pulse contour analysis) vs. Aortic Doppler ultrasound was evaluated on Stroke volume estimation (p=< 0.05). Compared with aortic Doppler ultrasound, Modelflow pulse contour analysis underestimated stroke volume by up to 25% after standing from a squat and 16% after thigh-cuff release (P<0.05).
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