Population
Rabbit papillary muscle and arterially perfused rabbit interventricular septum
Comparison
Variation in temperature, rate, and external… vs Baseline or alternative temperatures, rates, and…
Design
Preclinical
Authors
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No immediate clinical implications from isolated tissue; leaves open in vivo relevance of cooling on Ca2+ handling.
Abrupt cooling increases dP/dt in rabbit ventricular myocardium, likely due to increased membrane calcium concentration secondary to inhibited active sodium transport.
Langer et al. (1968) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: