Key result
Discontinuation of anticoagulation in a woman with combined factor V Leiden and prothrombin G20210A mutations led to a transmural myocardial infarction from coronary thrombosis 3 months later.
Case Report (n=1)
This case highlights the risk of severe arterial thrombosis, including myocardial infarction with normal coronary arteries, upon discontinuing anticoagulation in patients with combined thrombophilia.
No takes yet. Share an insight, caveat, or question.
May warrant caution discontinuing anticoagulation in combined thrombophilia; leaves open whether indefinite therapy prevents arterial events.
Gaspar et al. (2011) conducted a case report in Combined thrombophilia (factor V Leiden and prothrombin G20210A mutation) (n=1). Discontinuation of anticoagulation was evaluated on Transmural myocardial infarction caused by coronary thrombosis. Discontinuation of anticoagulation in a woman with combined factor V Leiden and prothrombin G20210A mutations led to a transmural myocardial infarction from coronary thrombosis 3 months later.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: