Key result
A young patient with combined factor V Leiden and prothrombin G20210A gene polymorphisms presented with myocardial infarction and a moderate atherosclerotic plaque in the left anterior descending artery.
Case Report (n=1)
This case highlights a potential relationship between prothrombotic gene mutations (factor V Leiden and prothrombin G20210A) and premature atherosclerosis leading to myocardial infarction.
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Should not yet change practice in young MI; leaves open whether combined mutations promote premature atherosclerosis.
Mugnolo et al. (2010) conducted a case report in Myocardial infarction and repeated thrombophlebitis (n=1). Heterozygous prothrombin G20210A mutation and homozygous factor V Leiden mutation was evaluated on Myocardial infarction and coronary atherosclerosis. A young patient with combined factor V Leiden and prothrombin G20210A gene polymorphisms presented with myocardial infarction and a moderate atherosclerotic plaque in the left anterior descending artery.
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