Why the study?
Does percutaneous transluminal coronary angioplasty affect the release of platelet activation markers in patients undergoing elective intervention?
Population
20 patients undergoing elective coronary angioplasty
Comparison
Percutaneous transluminal coronary angioplasty vs Baseline measurements
Design
Cohort
Follow-up
Immediately after the first balloon deflation
Authors
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Local coronary platelet activation precedes elective PTCA and declines after initial dilatation; hypothesis-generating for periprocedural thrombosis in stable CAD.
Does percutaneous transluminal coronary angioplasty affect the release of platelet activation markers in patients undergoing elective intervention?
Platelet activation occurs both systemically and in the coronary circulation before elective angioplasty, but marker levels tend to decline or remain unchanged after initial balloon deflation.
Korovesis et al. (2000) studied this question.
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