Why the study?
Does percutaneous transluminal coronary angioplasty stimulate platelet and prostaglandin activity in patients with coronary artery disease?
Population
9 patients with coronary artery disease undergoing percutaneous left anterior descending coronary artery…
Comparison
Percutaneous transluminal coronary angioplasty… vs Normal controls and pre-PTCA baseline state
Design
Cohort
Follow-up
Immediately after performance of PTCA
Authors
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PTCA may not acutely alter platelet activity in CAD; leaves open whether baseline coronary sinus PF4 elevation influences outcomes or merits intervention.
Does percutaneous transluminal coronary angioplasty stimulate platelet and prostaglandin activity in patients with coronary artery disease?
PTCA does not appear to acutely alter arachidonic acid metabolism or platelet activity in patients with coronary artery disease.
Stine et al. (1985) studied this question.
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