Key result
Maternal pre-eclampsia did not significantly change fetal global myocardial function assessed by Mod-MPI compared to healthy controls (0.44 vs 0.43; P=0.680).
Why the study?
Does maternal pre-eclampsia alter fetal global myocardial function assessed by Mod-MPI in fetuses without intrauterine growth restriction?
Population
72 fetuses at between 26 and 40 weeks' gestation without intrauterine growth restriction, including 40 from…
Comparison
Maternal pre-eclampsia (mild or severe) vs Healthy mothers (normal controls)
Design
Cross-sectional
Authors
Loading...
Mod-MPI shows no fetal myocardial change in pre-eclampsia without IUGR; leaves open clinical relevance of Doppler velocity shifts for prospective study.
Cross-Sectional (n=72)
Does maternal pre-eclampsia alter fetal global myocardial function assessed by Mod-MPI in fetuses without intrauterine growth restriction?
Absolute Event Rate: 0.44% vs 0.43%
p-value: p=0.680
Fetal global myocardial function assessed by Mod-MPI does not significantly change in mild or severe pre-eclampsia, though changes in Doppler velocities suggest increased cardiac afterload.
Api et al. (2008) conducted a cross-sectional in Pre-eclampsia (n=72). Maternal pre-eclampsia vs. Healthy mothers was evaluated on Modified myocardial performance index (Mod-MPI) (p=0.680). Maternal pre-eclampsia did not significantly change fetal global myocardial function assessed by Mod-MPI compared to healthy controls (0.44 vs 0.43; P=0.680).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: