Individualized single-drug therapy for hypertension may reduce side effects and preserve quality of life.
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Should not yet change hypertension prescribing; leaves open confirmation of individualized monotherapy benefits in prospective trials.
A new era in the management of high blood pressure is emerging. A number of drugs, acting by different mechanisms, are appropriate as individualized initial choices for treatment. The control of elevated blood pressure by single-drug therapy, if at all possible, will reduce the frequency of side effects and preserve a decent quality of life.
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James A. Schoenberger (1987) studied this question.
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