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January 1, 1988European Heart Journal

The Beta-Blocker Pooling Project (BBPP): subgroup findings from randomized trials in post infarction patients

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Why the study?

Does beta-blocker therapy reduce one-year all-cause mortality in post-infarction patients?

Population

13,679 post-infarction patients pooled from 9 randomized trials

Comparison

Beta-blocker therapy vs Placebo

Design

Meta-analysis

Follow-up

One-year

Discussion

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Implication

Supports routine beta-blocker use post-MI; confirms mortality benefit in updated Level 1 evidence.

Structured PICO

Does beta-blocker therapy reduce one-year all-cause mortality in post-infarction patients?

P
Population
13,679 post-infarction patients pooled from 9 randomized trials
I
Intervention
Beta-blocker therapy (seven different beta-blockers)
C
Comparator
Placebo
O
Outcome
One-year all-cause mortalityhard clinical

Beta-blocker therapy reduces one-year all-cause mortality by 24% in post-infarction patients, with the greatest absolute benefit observed in high-risk subgroups.

Cite This Study

A 1988 study studied this question.

synapsesocial.com/papers/6a830e777a9386604693c5fchttps://doi.org/10.1093/ehj/9.1.8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Beta-Blocker Pooling Project (BBPP): subgroup findings from randomized trials in post infarction patients1988 · 78 citations
  2. 2Effect of Beta-Blockade on Mortality among High-Risk and Low-Risk Patients after Myocardial Infarction1998 · 985 citations
  3. 3.BETA.-blockers Reduce the Incidence of Cardiac Events in Post-myocardial Infarction Patients.2000 · 6 citations
  4. 4Effectiveness of Beta-Blockers in Reducing Mortality and Recurrence After Myocardial Infarction: A Systematic Review of Contemporary and Foundational Evidence2025
  5. 5Beta-Blockers and Mortality After Myocardial Infarction1987 · 3 citations