Key result
Combined MR imaging and computational fluid dynamics simulations of the descending aorta demonstrated encouraging agreement with measured flow structures.
Why the study?
Does combined MR and CFD simulation accurately model flow in the human descending aorta compared to in vivo MRI?
Does combined MR and CFD simulation accurately model flow in the human descending aorta compared to in vivo MRI?
Combined MRI and CFD simulations can accurately model aortic flow and extract additional hemodynamic parameters like relative pressure and wall shear stress not measurable by MRI alone.
May enable extraction of unmeasurable aortic hemodynamics; leaves open prospective validation before clinical adoption.
A combined MR and computational fluid dynamics (CFD) study is made of flow in the upper descending thoracic aorta. The aim was to investigate further the potential of CFD simulations linked to in vivo MRI scans. The three-dimensional (3D) geometrical images of the aorta and the 3D time-resolved velocity images at the entry to the domain studied were used as boundary conditions for the CFD simulations of the flow. Despite some measurement uncertainties, comparisons between simulated and measured flow structures at the exit from the domain demonstrated encouraging levels of agreement. Moreover, the CFD simulation allowed the flow structure throughout the domain to be examined in more detail, in particular the flow separation region in the distal aortic arch and its influence on the downstream flow during late systole. Additional information such as relative pressure and wall shear stress, which could not be measured via MRI, were also extracted from the simulation. The results have encouraged further applications of the methods described. J. Magn. Reson. Imaging 2001;13:699-713.
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Wood et al. (2001) studied Aortic flow. Combined MR imaging and computational fluid dynamics (CFD) simulation vs. In vivo MRI scans was evaluated on Agreement between simulated and measured flow structures. Combined MR imaging and computational fluid dynamics simulations of the descending aorta demonstrated encouraging agreement with measured flow structures.
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