Key result
Intramuscular frusemide is linked to clinical improvement and marked diuresis in infants with heart failure.
Observational (n=13)
Answers are grounded in this paper and cite their sources.
Twelve infants with heart failure and one with perinatal oedema were treated with intramuscular frusemide (1·0-1·25 mg/kg). Frusemide was found to be a safe effective diuretic in infants with heart failure, resulting in clinical improvement, marked excretion of water, sodium, and chloride, with a lesser and more variable effect on potassium excretion. Complications were uncommon with this dose. The drug is most effective in acute pulmonary oedema or acute worsening of heart failure, but day-to-day control of persistent heart failure is more easily obtained by using repeated doses of oral or intramuscular frusemide plus, if needed, aldactone A or triamterene.
No takes yet. Share an insight, caveat, or question.
Harriet Richardson (1971) conducted an observational in Heart failure and perinatal oedema in infancy (n=13). Intramuscular frusemide was evaluated on Clinical improvement and excretion of water, sodium, chloride, and potassium. Intramuscular frusemide in 13 infants with heart failure or perinatal oedema produced clinical improvement and marked water, sodium, and chloride excretion.
Synapse has enriched 10 related papers. Consider them for comparative context: