Why the study?
Does a combined immunoaffinity cDNA-RNA hybridization assay improve the detection of hepatitis A virus compared to radioimmunoassay in clinical fecal specimens?
Population
23 fecal specimens collected from individuals during week 1 of symptoms due to hepatitis A
Comparison
Combined immunoaffinity cDNA-RNA hybridization… vs Radioimmunoassay
Design
Other
Authors
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May improve HAV detection in fecal specimens; hypothesis-generating pending clinical validation.
Does a combined immunoaffinity cDNA-RNA hybridization assay improve the detection of hepatitis A virus compared to radioimmunoassay in clinical fecal specimens?
A novel combined immunoaffinity cDNA-RNA hybridization assay demonstrates higher sensitivity than standard radioimmunoassay for detecting hepatitis A virus in clinical fecal specimens.
Jansen et al. (1985) studied this question.
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