July 1, 1981The Journal of Infectious Diseases

Susceptibility of Monkeys to Human Hepatitis A Virus

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Population

Stump-tailed monkeys (Macaca speciosa), newly caught and without antibody to hepatitis B virus (HAV), n=3

Design

Preclinical

Authors

JMJiang-sen MaoZhejiang Academy of Medical Sciences YGY. Y. GoThe University of Tokyo HHH.Y. HuangNew York University

Discussion

Member takes

Implication

Supports stump-tailed monkeys as an HAV model; leaves open translation to human vaccine or therapy development.

Structured PICO

Population

Stump-tailed monkeys (Macaca speciosa), newly caught and without antibody to hepatitis B virus (HAV), n=3

Intervention

Infection with human hepatitis A virus

Outcome

Susceptibility to infection (elevation in serum glutamic pyruvic transaminase, lactate dehydrogenase, and its type 5 isoenzyme; development of antibody to HAV; shedding of HAV antigen in feces)surrogate

Stump-tailed monkeys can serve as a susceptible animal model for human hepatitis A virus infection.

Cite This Study

Mao et al. (1981) studied this question.

synapsesocial.com/papers/6a831965ef922d2380582aba https://doi.org/10.1093/infdis/144.1.55

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Susceptibility of Monkeys to Human Hepatitis A Virus

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Susceptibility of Monkeys to Human Hepatitis A Virus

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider