Population
Owl monkeys (Aotus trivirgatus)
Design
Preclinical
Follow-up
Up to 5.5 weeks
Authors
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Owl monkey findings suggest possible intestinal HAV replication in humans; hypothesis-generating and should not yet change clinical practice.
Oral inoculation of owl monkeys with HAV demonstrates viral replication in the liver and suggests the intestine as an additional site of replication.
Asher et al. (1995) studied this question.
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