October 27, 2010Emerging infectious diseasesOpen Access

Enterovirus 71 Infection with Central Nervous System Involvement, South Korea

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Population

94 patients with PCR-confirmed enterovirus 71 infection with central nervous system involvement in South…

Design

Cohort

Follow-up

until discharged or for 3 weeks if duration of…

Authors

WRWi‐Sun RyuE Ink (South Korea)BKByunghak KangNovartis (United States)JHJi‐Young HongCHA Bundang Medical Center

Discussion

Member takes

Implication

Monitor EV71 CNS cases with brainstem MRI changes for collapse or sequelae; observational data leave optimal interventions open.

Structured PICO

Population

94 patients with PCR-confirmed enterovirus 71 (EV71) infection with central nervous system involvement (meningitis or encephalitis) in South Korea during 2009. Mean age 46 months, 63% boys.

Outcome

Patient outcome classified as no sequelae, mild sequelae, severe sequelae, or deathhard clinical

The 2009 EV71 outbreak in South Korea was predominantly caused by the C4a genotype and had a relatively low case-fatality rate, though it still caused severe neurologic sequelae and cardiopulmonary collapse in a small number of patients.

Cite This Study

Ryu et al. (2010) studied this question.

synapsesocial.com/papers/6a8334fe78944653d1e8ec22 https://doi.org/10.3201/eid1611.100104

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Enterovirus 71 Infection with Central Nervous System Involvement, South Korea

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Enterovirus 71 Infection with Central Nervous System Involvement, South Korea

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider