Why the study?
Hyperinsulinism is widely associated with neonatal cardiac hypertrophy that cannot be distinguished from HCM on echocardiography, yet it is currently not acknowledged as a cause in textbooks or registry publications.
Population
Neonates and infants with hyperinsulinemic diseases or cardiac hypertrophy
Design
Literature review
Authors
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Hyperinsulinism warrants consideration in neonatal HCM differentials; leaves open causal links and screening utility pending prospective studies.
Hyperinsulinism is associated with cardiac hypertrophy in a broad range of hyperinsulinemic diseases and should be considered in the differential diagnosis of neonatal hypertrophic cardiomyopathy.
Stegeman et al. (2019) studied this question.
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