Population
Escherichia coli expressing human P68 protein kinase under control of the bacteriophage T7 promoter
Comparison
Expression of wild-type P68 protein kinase vs Expression of mutant P68 protein
Design
Preclinical
Authors
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Confirms intrinsic P68 activity in prokaryotic systems; leaves open relevance to human cardiovascular disease.
The successful functional expression of human P68 protein kinase in E. coli demonstrates its intrinsic capacity for autophosphorylation independent of other eukaryotic proteins.
Barber et al. (1991) studied this question.
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