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September 1, 2017Current Directions in Biomedical EngineeringOpen Access

Numerical simulation of pulsatile flow through a coronary nozzle model based on FDA’s benchmark geometry

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Population

FDA benchmark generic nozzle geometry scaled down to coronary dimensions (D inlet = 12 mm to 3 mm)

Comparison

Pulsatile computational fluid dynamics simulations vs Steady state CFD simulations

Design

Preclinical

Authors

MSMichael StiehmLund UniversityCWCarolin WüstenhagenUniversitätsmedizin RostockSSStefan SiewertInstitute for ImplantTechnology and Biomaterials

Discussion

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Implication

Validates computationally cheaper steady-state simulations for coronary hemodynamics when only time-averaged values are needed.

Structured PICO

P
Population
FDA benchmark generic nozzle geometry scaled down to coronary dimensions (D inlet = 12 mm to 3 mm)
I
Intervention
Pulsatile computational fluid dynamics (CFD) simulations (Re = 500, Wo = 2.065)
C
Comparator
Steady state CFD simulations
O
Outcome
Time averaged wall shear stress and shear stress valuessurrogate

Steady state simulations are valid for hemodynamic analyses of coronary nozzle models if only time-averaged values are needed, potentially saving computational costs.

Cite This Study

Stiehm et al. (2017) studied this question.

synapsesocial.com/papers/6a8351683f5d08169db48670https://doi.org/10.1515/cdbme-2017-0163
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Computational Fluid Dynamics Simulation of Reynolds Stress Frequencies in the FDA Nozzle2024
  2. 2Computational fluid dynamics modeling of coronary artery blood flow using OpenFOAM: Validation with the food and drug administration benchmark nozzle model2024 · 3 citations
  3. 3Benchmark for Numerical Models of Stented Coronary Bifurcation Flow2018 · 3 citations
  4. 4CFD-Based Extensional Stress and Hemolysis Risk Evaluation in the U.S. Food and Drug Administration (FDA) Benchmark Nozzle Configurations2025 · 2 citations
  5. 5Numerical Investigation of Pulsatile Blood Flow and Hemodynamic Indicators in Stenosed Arteries2026