Poliovirus replication in human mononuclear phagocyte cell lines is dependent on the stage of cell differentiation, providing a model for studying poliovirus-leukocyte interactions.
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Differentiation stage modulates poliovirus permissiveness in phagocyte lines; leaves open relevance to human leukocytes pending primary-cell validation.
Roivainen et al. (1989) studied this question.
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