The outbreak of poliomyelitis in a vaccinated population in Finland was likely facilitated by the antigenic properties of an unusual type 3 poliovirus strain unrelated to vaccine strains.
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May explain breakthrough poliomyelitis in vaccinated populations; leaves open whether antigenic surveillance should inform polio vaccine updates.
Virus isolated from an outbreak of poliomyelitis in Finland has been examined serologically and at the molecular level. The causative agent was an antigenically unusual strain of type 3 poliovirus, which was unrelated to the strains used to manufacture either live or killed poliovaccines. It is likely that the antigenic properties of the virus played a part in establishing a limited outbreak of poliomyelitis in a vaccinated population.
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Magrath et al. (1986) studied this question.
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