Why the study?
Does infusion of cationic amino acids (arginine, lysine, ornithine) increase forearm blood flow in normal male subjects compared to equiosmolar sodium chloride?
Population
8 normal male subjects
Comparison
Infusion of L and D isomers of arginine, lysine… vs Equiosmolar sodium chloride solutions
Design
Other
Authors
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Arginine vasodilation exceeds osmolality without stereospecificity; challenges NO-dependent mechanisms and leaves open clinical relevance.
Does infusion of cationic amino acids (arginine, lysine, ornithine) increase forearm blood flow in normal male subjects compared to equiosmolar sodium chloride?
The vasodilator effect of arginine in the resting forearm is not stereospecific and is likely related to physical properties rather than increased nitric oxide production.
Rhodes et al. (1996) studied this question.
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