Why the study?
Does L-arginine infusion reduce blood pressure and vascular resistance compared to L-lysine and saline in healthy subjects?
Population
Healthy subjects
Comparison
L-arginine infusion vs Saline and L-lysine infusions
Design
Other
Authors
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L-arginine may induce specific vasodilation in healthy subjects; leaves open therapeutic translation and requires confirmation in cardiovascular disease.
Does L-arginine infusion reduce blood pressure and vascular resistance compared to L-lysine and saline in healthy subjects?
L-arginine infusion induces vasodilatation that cannot be explained by the non-specific effects of cationic amino acids, indirectly supporting its role in increasing nitric oxide synthesis.
Smulders et al. (1997) studied this question.
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