Why the study?
Does intravenous L-arginine infusion improve renal plasma flow compared to D-arginine in healthy young men?
Population
20 young, healthy male white subjects (age 26±2 years)
Comparison
Intravenous administration of L-arginine at… vs Intravenous administration of D-arginine at…
Design
RCT, randomized cross-over, double-blind
Follow-up
30 min
Authors
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L-arginine infusion at 100 mg/kg validates a probe for renal endothelial function in healthy men; extends its utility for targeted vascular studies without systemic effects.
Does intravenous L-arginine infusion improve renal plasma flow compared to D-arginine in healthy young men?
L-arginine infusion at 100 mg/kg for 30 minutes is a suitable tool to assess endothelium-dependent vasodilation of the human renal vasculature without causing systemic hemodynamic changes.
SCHLAICH et al. (2000) studied this question.
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